Ontario Biomedical Exam – Sample Questions

1. In assessing a patient with suspected myocardial infarction, understanding the supply areas of the coronary arteries is crucial. If a patient presents with symptoms indicative of an infarction in the posterior part of the heart, which coronary artery is most likely involved?

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2. What is the main role of the atrioventricular node (AV node) in cardiac conduction?

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3. A teenage patient exhibits delayed puberty with minimal development of secondary sexual characteristics. Which endocrine gland should primarily be evaluated for potential dysfunction?

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4. What is the origin of the liver and pancreas during embryological development?

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5. What is the primary immune function of the GALT (gut-associated lymphoid tissue) in the gastrointestinal tract?

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6. When assessing a patient with suspected bone marrow dysfunction, which imaging technique is essential for evaluating the structure and viability of bone marrow?

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7. At what stage of embryonic development do hematopoietic stem cells first appear?

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8. What type of cell is primarily responsible for cellular immunity?

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9. In managing a patient with chronic inflammation, how might understanding arachidonic acid metabolism be beneficial?

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10. In assessing a patient with an impaired ability to sweat, what aspect of temperature regulation should be carefully monitored during physical activity?

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11. Where is spongy bone most likely found within the typical long bone?

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12. Which substance is a primary energy source for muscle contraction during the first few seconds of high-intensity exercise?

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13. What is the primary function of the somatic part of the peripheral nervous system?

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14. Which infectious agent is known to cause a chronic degenerative neurological condition called progressive multifocal leukoencephalopathy (PML)?

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15. What is the role of the phrenic nerve within the thoracic cavity?

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16. What change occurs in the respiratory system as a result of long-term aerobic exercise?

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17. Which hormone influences libido and is commonly associated with the modulation of sexual desire?

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18. What factor can inhibit milk production despite adequate prolactin levels?

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19. Where are the kidneys located relative to the peritoneum?

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20. A patient with a known mutation in the CYP24A1 gene presents with recurrent kidney stones. What is the most likely pathophysiological mechanism?

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